Endocrine Abstracts

Objective: Randomized trials demonstrated a lower risk of cardiovascular (CV) events with sodium – glucose cotransporter-2 inhibitors (SGLT-2i) in patients with type 2 diabetes(T2D) at high CV risk. SGLT2-i should be considered as a valuable therapy in T2D with established atherosclerotic cardiovascular disease (ASCVD) or heart failure (HF). We analyzed the effects of cardiovascular function of SGLT 2 inhibitors in T2D with ASCVD or HF compared with dipeptidyl peptidase-4...

Objective: Dapagliflozin, sodium-glucose cotransporter-2 (SGLT-2) inhibitor, reduces hyperglycemia and body weight by inhibiting renal glucose reabsorption. However, only a few studies have shown the efficacy of dapagliflozin in type 2 diabetic patients. We evaluated the efficacy and safety of body weight reduction of dapagliflozin in real practice with type 2 diabetes in Korea.Methods: This is a retrospective, observational study, data from 61 patients ...

Objective: This study was performed to determine the impact on quality of life and sleep impairment of painful diabetic peripheral neuropathy (PDPN).Research design and method: The study pool consisted of 200 randomly selected peoples with type 2 diabetic peripheral neuropathy. PDPN was diagnosed using visual analogue scales (VAS) and medical history. The patients were asked to answer the Brief Pain Inventory-Short Form (BPI-SF), Medical Outcomes Study S...

Introduction: Occurrence of follicular thyroid carcinoma (FTC) is limited almost within thyroid gland, but distant metastasis is discovered uncommonly as first presentation. We experienced a rare case about recurrent bone metastasis of FTC with unknown primary site.Case report: A 58-year-old woman complained about back pain for 3 years. A 5 cm sized mass in right 8th posterior rib was discovered and performed resection. The result of pathology was bone m...

Objective: Dapagliflozin, sodium-glucose cotransporter-2 (SGLT-2) inhibitor, reduces hyperglycemia and body weight by inhibiting renal glucose reabsorption. However, only a few studies have shown the glycemic efficacy on a combination of dapagliflozin in type 2 diabetic patients in Korean. We evaluated the efficacy and safety of glucose control on a combination of dapagliflozin in people with type 2 diabetes in Korea.Methods: This is a retrospective, obs...

Current guidelines on cardiovascular (CV) disease prevention recommend targeted management after assessment of CV risks using many of available method even if the patient is asymptomatic. This study was performed to explore how CV high-risk is differently detected between two distinct methods: non-invasive test (NIT) and risk calculation and how the awareness of CV high-risk impacts physician and patient behavior for risk management in diabetes patient.A...

Background: Although sclerostin (SOST) and Dickkopf-related protein 1 (DKK1) are major regulators in bone metabolism, the associations between these soluble Wnt antagonists and osteoporotic fracture (OF) in Asians, who may have distinct biologic characteristics with Caucasians, are inconclusive. Furthermore, there have been no clinical studies separately considering non-vertebral and vertebral fractures in terms of the blood levels of SOST and DKK1.Metho...